p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies
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چکیده
منابع مشابه
p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies
Mallory-Denk bodies (MDBs) are hepatocytic protein aggregates found in steatohepatitis and several other chronic liver diseases as well as hepatocellular carcinoma. MDBs are mainly composed of phosphorylated keratins and stress protein p62/Sequestosome-1 (p62), which is a common component of cytoplasmic aggregates in a variety of protein aggregation diseases. In contrast to the well-established...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2016
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0161083